Research/Boosting innate immunity
From Poultry Hub
Title: Boosting innate immunity and use of cytokines for the enhancement of vaccine efficacy through manipulation of the immune system
Project Leader: Andrew Bean at CSIRO funded by Poultry CRC (Project 03-16c)
Duration of Project: Now completed (24 December 2003 to 24 December 2009)
Contents |
Project overview
Immunosuppressive viral diseases threaten the poultry industry causing increased morbidity and mortality resulting in economic loss of production. The impact of this is generally through the chickens' increased susceptibility to secondary infections and sub-optimal response to vaccinations. The objective here is to assess the nature of the immune response during infection and assess the ability of chicken cytokines to enhance disease resistance and augment immunocompetence in the face of infection.
Project objectives
- Assess the cytokine profiles during infections; and
- Based on these results, make a rational determination of the appropriate cytokines to act as a potential therapeutic or vaccine adjuvants.
Project progress
This project has been completed and the Final Report is available from the Poultry CRC.
