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[[Image:AAHL-exterior.jpg|right|thumb|300px|CSIRO's Australian Animal Health Laboratory]]
'''Title:''' Phage-displayed peptides are antimicrobial towards ''Campylobacter jejuni'' in chickens

'''Project Leader:''' [[Bishop-Hurley, Sharon|Sharon Bishop-Hurley]] at [[Organisations#Commonwealth_Scientific_and_Industrial_Research_Organisation_.28CSIRO.29_Livestock_Industries|CSIRO]] funded by [[Poultry CRC]] (Project 06-09)
  	
'''Duration of Project:'''
1 July 2006 to 1 December 2009

===Project overview===
''Campylobacter jejuni'' is a leading cause of zoonotic food-borne illnesses in humans, with chicken meat being a major source of this infection. Current strategies for reducing the persistence and colonisation of this microorganism in the gastrointestinal tract of chickens are proving ineffective. Therapeutics targeted at reducing ''C. jejuni'' from the gastrointestinal tract of chickens would limit the incidence of this food-borne illness in humans.

====Project objectives====
*Use peptide phage-display to target cell surface receptors on ''C. jejuni'' involved in colonisation and persistence in the gastrointestinal tract of chickens; and
*Test phage peptides for specific antimicrobial activity against ''C. jejuni in vitro''.

===Project progress===
A subtractive phage display approach is currently being used to affinity select for peptides binding to the cell surface of ''C. jejuni.''

== See also ==

*[[Campylobacter]] 
*[[Darkling Beetles]] 
*[[Digestive system]] 
*[[Food safety principles]]

[[Category: Research_&_Development]] [[Category:Anatomy_and_physiology]] [[Category:Chicken_meat_industry]] [[Category:Bird_health_and_disease]] [[Category:Food_safety]]